PRO-ACT logo RegisterLog in Neurological Clinical Research Institute
Welcome to the
Pooled Resource Open-Access ALS Clinical Trials Database
PRO-ACT provides users with easy access to:
  • Over 11,600 fully anonymized subject records
  • Placebo and treatment-arm data from 29 Phase II/III clinical trials
  • Demographic, lab, medical and family history, and other data elements
  • More than 10 million longitudinally collected data points

The popularity of the project is illustrated by the following statistics:

  • Registed users: 2749
  • Countries: 83
  • Downloads: 18853

We thank everyone who has contributed to the creation of PRO-ACT including the companies, the researchers, and most of all the ALS patients, past and present, around the world, to whom the PRO-ACT initiative is dedicated:

  • ALS Therapy Alliance
  • Amylyx Pharmaceuticals, Inc.
  • Cytokinetics, Inc.
  • Knopp Biosciences
  • Neuraltus Pharmaceuticals, Inc.
  • Neurological Clinical Research Institute, Massachusetts General Hospital
  • Northeast ALS Consortium
  • Novartis
  • Prize4Life Israel
  • Regeneron Pharmaceuticals, Inc.
  • Sanofi
  • Teva Pharmaceutical Industries, Ltd.
  • The ALS Association